Likewise, enhanced antibody response to C. trachomatis EB and chlamydial GroEL (C. trachomatis Hsp60 homolog, CT110) protein is associated with trachoma (Skwor et al., 2010) subfertility (Karinen et al., 2004), infertility, especially tubal factor infertility, a manifestation of persistent C. trachomatis infection (Toye et al., 1993; Witkin et al., 1998; Tiitinen et al., 2006). This evidence concerns the gene HSPD1 and Infertility.