BCL2 and urogenital neoplasm: Recently, Bcl-2 expression has been observed in urinary bladdertumors of 63% of patients with low gradedisease; since Bcl-2 expression was found to beabsent in normal adjacent bladder tissues, a hypothesishas been proposed that the expressionof this gene may be correlated to a very earlystage of bladder carcinogenesis (10).