Gazzaniga et al. suggest that the increasein the level of Bax gene product contributingto the formation of heterodimers with Bcl-2protein or Bax homodimers, may be able torepair the apoptotic removal of tumoral cells,therefore preventing the malignant growthand metastatic progression of bladder cancer(17). The gene discussed is BAX; the disease is urinary bladder cancer.