2.3. Protective Effects of BL153 on Obesity-Induced Renal Damage Is Associated with the Upregulation of Renal Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α (PGC-1α), NAD(P)H Quinone Oxidoreductase 1 (NQO1), and Hexokinase II (HK II) Expression. Here, PPARGC1A is linked to obesity due to melanocortin 4 receptor deficiency.