PSIP1 and HIV-1 infection: Pleiotropic functions of hLEDGF/p75 were suggested in HIV-1 infection including promotion of nuclear accumulation of PIC (Cherepanov et al., 2003, 2004; Maertens et al., 2003; Llano et al., 2004b; Ciuffi et al., 2005; Vanegas et al., 2005; Van Maele et al., 2006), selection of HIV-1 integration sites and enhancement of proviral integration (Bukrinsky, 2004; Llano et al., 2004a, 2006a; Emiliani et al., 2005).