NOS2 and Alzheimer disease: In this model of AD, EGCG (1, 10, and 100 μM) also prevented astrocytes activation and inflammatory factors including TNF-α, IL-1β, macrophage colony-stimulating factor, soluble intracellular adhesion molecule-1, IL-6, inducible nitric oxide synthase (iNOS) and COX-2 [94,95].