CTSC and Haim-Munk syndrome: Due to the implication of human cathepsin C in Papillon–Lefevre disease and Haim-Munk syndrome or inflammatory diseases, and the involvement of its malarial ortholog DPAP1 in the hemoglobin digestion pathway, both enzymes are considered interesting medical targets (Deu et al. 2010; Guay et al. 2010; Klemba et al. 2004).