SMN1 and autoimmune hepatitis: The longest standing criteria, “Paris criteria” suggest that patients with overlap have PBC defined by: (i) alkaline phosphatase levels at least twice the upper limit of normal, (ii) positive AMA, and (iii) a liver biopsy showing florid bile duct lesion and AIH defined by (i) alanine transaminase levels at least five times the upper limit of normal, (ii) Immunoglobulin G levels at least twice the upper limit of normal or a positive anti-SMA, and (iii) a suggestive liver biopsy [51].