ESR1 and neoplasm: The decrease in Ki-67 positivity in benign cells and malignant cell components was found consistently by ER/PR positivity status (ER+PR+, ER+/PR−, ER−PR−) and tumor stage at diagnosis (Stage I and II+) in the green tea group but not in the control group although we did not perform formal statistical testing of differences by these subgroups because of small numbers (Figure 2).