As already seen for EqTx-II, noncytotoxic concentrations of Bc2 (0.1 mg/mL) were seen to improve cytotoxicity of the chemotherapeutics cytosine arabinoside, doxorubicin, and vincristine, utilized at low concentrations, on GBM cells. The gene discussed is CHMP2A; the disease is glioblastoma.