PDGFRA and cancer: Several other bioinformatic predicted targets of miR-199a-3p, such as breast cancer anti-estrogen resistance 3 (BCAR3), cell cycle associated protein 1 (CAPRIN1), cell division cycle 42 (Cdc42), Yes-associated protein 1 (Yap1), and platelet-derived growth factor receptor, alpha polypeptide (PDGFRA) can also activate AKT.