In vivo studies showed human embryonic kidney 293 cells (HEK 293) stably transfected and expressing IL-24 (HEK293-IL24) when mixed with human A549 lung tumor cells and implanted into nude mice resulted in suppression of tumor growth when compared to tumor growth in mice implanted with mixture of unmodified parental HEK293 and A549 cells [66]. The gene discussed is IL24; the disease is neoplasm.