Further investigation of the association of the DP6 supertype with leukemia (45) found that, of the seven alleles included in this supertype, only DPB1*06:01 was significantly associated with childhood leukemia (corrected p-value = 0.02), including total ALL, AML, BCP-ALL, Pro-B ALL, and T-ALL. Here, HLA-DPB1 is linked to acute lymphoblastic leukemia.