However, such genes as IFI27 (−4.38), SLC22A7 (−3.97), IFIT1 (−3.91), TGFB3 (−3.71), and IFN-α induced (−3.72) also had stronger suppression at the transcript level in HCC-R tumor tissues. The gene discussed is TGFB3; the disease is hepatocellular carcinoma.