Interestingly, among the over-expressed genes (Table 2), MT2A (metallothionein 2A) and CCNE1 (cyclin E1) are associated not only with breast cancer, but also with cadmium induction [19,41-43] suggesting that the microarray analysis is identifying genes relevant to both cadmium exposure and breast cancer. The gene discussed is CCNE1; the disease is breast carcinoma.