Therefore to test expression localization, we compared our Ad5ROBO4 versus Ad5CMV vectors in a nine organ panel harvested from tumor bearing immunodeficient Rag2−/− mice (negative littermate mice derived from hCAR:Rag2−/− × Rag2−/− matings, Materials and Methods) (Figures 2A and 2C). This evidence concerns the gene RAG2 and neoplasm.