CLL cell adhesion to TNFα-stimulated BMSC was significantly reduced from 128.9% (±7.3%) to 94.1% (±7.9%) using 9-15c cells, and from 143.9% (±16.9%) to 100.7% (±10.1%) using CLL-MSC (Figure 1A). This evidence concerns the gene TNF and B-cell chronic lymphocytic leukemia.