Since we have analysed adult-young CDM patients where muscle histopathological alterations might be due more to the developmental defects than to the degenerative process, it is possible that CUGBP1 expression in our DM1-CDM muscles appears to be similar to DM1-E1 more than to DM1-E2. Here, CELF1 is linked to myotonic dystrophy type 1.