Our western blotting analysis of CUGBP1 protein expression confirms that CUGBP1 is overexpressed in DM1 muscle biopsies however the increase is evident only in DM1-E2 while CUGBP1 protein levels in DM-E1 and DM1–CDM appear to be similar to those observed in healthy controls. This evidence concerns the gene CELF1 and myotonic dystrophy type 1.