IDH1 and acute myeloid leukemia: While the frequency of IDH1 non-R132 mutations were divided into 6 subtypes of AML: M1 35.7% (5/14), M2 7.9% (9/114), M3 6.8% (3/44), M4 6.8% (5/74), M5 9.2% (7/76) and M6 8.3% (2/24).