It would be worthwhile to comment that comparison of the two main types, shows that the oligodendroglioma/astrocytoma-rich main type exhibited enhanced activities of exogenous hormone-stimulated growth and PAR1 signaling activity, while up-regulated gene profiles associated with the glioblastoma-rich main type, involved cell cycle/mitotic pathways, hypoxia, tumor necrosis, and NF-κB pathway signaling, consistent with a more malignant and aggressive tumor type. This evidence concerns the gene NFKB1 and neoplasm.