We also verified the array result in a separate, larger cohort consisting of 115 IPF lung samples and 154 normal histology controls, by using nCounter® expression analysis and demonstrated that COMP mRNA was significantly increased in IPF lungs (8.8 Fold change, P- value = <0.05 compared to normal histology lungs) (Figure 1C). Here, COMP is linked to idiopathic pulmonary fibrosis.