Candidate gene studies of hypertension and BP have implicated several interactions between alcohol and genes [ADH2 (Sen Zhang et al., 2013), ALDH2 (Chang et al., 2012; Nakagawa et al., 2013; Wang et al., 2013), SOD2 (Nakagawa et al., 2013), LEPR (Sober et al., 2009), ApoE (Leite et al., 2013), CYP11B2 (Pan et al., 2010), NADH2 (Kokaze et al., 2004, 2007), GNB3 (Polonikov et al., 2011), and ADM (Chen et al., 2013)]. Here, CYP11B2 is linked to hypertensive disorder.