During Th1-type (=cell-mediated) immune response, the pro-inflammatory cytokines interferon-γ (IFN-γ), and interleukin-2 (IL-2) are produced by activated T and natural killer cells to mount an effective response against pathogens and tumor cells, while allergic Th2-type cell responses are characterized by cytokines IL-4, IL-5, and IL-13 (Barth et al., 2003; Romagnani, 2004). Here, IL2 is linked to neoplasm.