DYRK1A and Dravet syndrome: Considering that DYRK1A is involved in neurodevelopment and altered in DS (Tejedor et al, 1995; Guimera et al, 1996; Song et al, 1996; Tejedor & Hämmerle, 2011), we investigated the role of DYRK1A in NPCs and neurons derived from Twin-DS-iPSCs.