16In addition, according to analysis of the correlation between expression level of LRPPRC and patients’ characteristics, one of the interesting findings was that expression level of LRPPRC was significantly associated with the depth of tumor invasion, lymph nodes metastasis (N stage), and distant metastasis (M stage) (Table 1).Tian et al. [11] reported that the lung adenocarcinoma cell line A549, treated with LRPPRC, had high invasive ability. The gene discussed is LRPPRC; the disease is lung adenocarcinoma.