A mid-2013 publication describes the start of a well-designed multicenter RCT of lower-BMI insulin-dependent patients who will undergo RYGB plus standard medical treatment, if needed, compared with controls who will receive only standard T2DM treatment; this RCT, the DiaSurg Trial, with a target size of 400 participants, will provide long-term comparative data (8 years) on T2DM outcomes following bariatric surgery vs conventional diabetes care [76]. Here, INS is linked to diabetes mellitus.