Several putative inflammatory biomarkers in plasma or serum like C-reactive protein (CRP)[34,35], pulmonary and activation-regulation chemokine (PARC/CCL-18)[36], and fibrinogen[37] have been tested for their ability to predict all-cause and COPD-related mortality in patients with various stages of COPD. The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.