When compared trauma + sepsis group with trauma group, we found statistically highly significant difference (P < 0.01) in IL-8, IL-10 and statistically significant difference (P < 0.05) in TNF-alpha concentrations; mean values of IL-8 were 230-fold, IL-10 42-fold, and TNF-alpha 17-fold higher in trauma + sepsis group. Here, CXCL8 is linked to Sepsis.