Furthermore, the renilla luciferase activity in vv811WT- or vv811ΔA49-infected cells was not lower than that in mock-infected HEK293T cells after a 12-h infection (data not shown), indicating that the inhibition of NF-κB by these viruses is not due to a general shutdown of transcription or translation by the virus. The gene discussed is NFKB1; the disease is infection.