PLOD1 and ovarian hyperstimulation syndrome: The importance of the endogenous LH level around the time of trigger is strengthened by the recent observation that use of a dual trigger (GnRHa trigger and a bolus of hCG 1000 IU) for those women with a peak E2 < 4,000 pg/mL was associated with an improvement in live birth rate from 30.9% to 52.9% with only one case of mild OHSS reported [28].