Of the 42 common Significant hypermethylated genes unique to Stages I and III, GALR1, NID2 have been identified as highly methylated in NSCLC [46,55], PAX7 has been identified in lung cancer but not reported with methylation [57], though PAX family genes have been previously reported being methylated in cancer [58]. The gene discussed is NID2; the disease is lung carcinoma.