Furthermore, in the Guangxi NPC GWAS (12), where high resolution HLA genotyping was performed, multivariate analyses suggested that associations were driven by HLA-A*1101 and that presence of glutamine at amino acid position 62 of the HLA-A gene (which marks HLA-A*11) was strongly associated with NPC risk providing a biological basis for the SNP-based associations reported. This evidence concerns the gene HLA-A and nasopharyngeal carcinoma.