CD79A and nasopharyngeal carcinoma: In the future, it will be important to evaluate genetic factors associated with anti-EBV EBNA-1 and VCA IgA responses because (1) EBNA-1 and VCA are the antigens for which strong and consistent associations with risk of NPC development have been observed and (2) IgA responses (rather than IgG responses) are thought to better reflect chronic EBV reactivation at mucosal surfaces believed to be required for NPC development.