COMT and Borderline personality disorder: In our previous work we have reported that increased methylation of 5-hydroxytryptamine (serotonin) receptor 2A (1.24 fold), glucocorticoid receptor gene (NR3C1) (1.22 fold), monoamine oxidase A (1.05 fold), monoamine oxidase B (1.08 fold) and soluble COMT (1.07 fold) occurs in BPD [9].