At 24 h, administration of anti-PSGL-1 antibody prevented reduction of blood platelets (Figure 5 B), but did not affect the plasma TXB2 levels (Figure 5 C), suggesting anti-PSGL-1 antibody directly disrupts interaction of between neutrophils and platelets and prevents thrombocytopenia. This evidence concerns the gene SELPLG and Thrombocytopenia.