In exploring associations between fourteen previously discovered non-HLA T1D candidate SNPs and the development of IA and progression to T1D in the prospective DAISY cohort, we found that C1QTNF6 (rs229541) predicts IA but not progression to T1D, demonstrating stage-related heterogeneity. The gene discussed is C1QTNF6; the disease is type 1 diabetes mellitus.