RET and differentiated thyroid carcinoma: RET/PTC (Rearranged in Transformation/Papillary Thyroid Carcinoma) re-arrangement, BRAF (V-Raf murine sarcoma viral oncogene homolog B) and RAS (Rat Sarcoma viral oncogene homolog) point mutations are frequently observed in papillary thyroid cancer (Mitsutake et al., 2006; Knauf and Fagin, 2009).