In general, expanded populations of autoreactive CD57+ T cells are associated with more severe disease – Wegener’s granulomatosis (65), pars planitis (25), multiple sclerosis (MS) (66), type I diabetes mellitus (67), Graves’ disease (68), and rheumatoid arthritis (RA) (69), amongst others. Here, B3GAT1 is linked to rheumatoid arthritis.