CXCR3 and infection: To identify the mechanism of recruitment of CD103+ DC in the infected mucosa, we performed functional studies in vivo with CXCL10: CXCL10 was one of the most strongly upregulated chemokines in the IEC during neonatal mouse infection and the mRNA for its receptor, CXCR3, was found to be expressed in CD103+ DC isolated from neonates and adult mice (Figure 5, A).