To detect levels of Hif-α signaling in Mm infection we utilized in situ hybridization for the known Hif-α target phd3 (Figure S1A and S1B) and the transgenic line Tg(phd3:GFP)i144 (Figure 1A and 1B) [16], [25]. This evidence concerns the gene EGLN3 and Miyoshi myopathy.