HSPH1 and neoplasm: When we tested these peptides for their potential to induce in vitro tumor reactive CTLs in spleen cells derived from BALB/c mice immunized with the HSP105 peptides, only the HSP105 24-1 peptide-induced CTLs showed specific cytotoxicity against C26 tumors (HSP105+, H-2Kd) (Fig. 2).