In the TectaC1509G/+ mouse, a mouse with a missense mutation in the ZA domains of Tecta that causes a mild–moderate (20–60 dB), progressive form of deafness in a Turkish family, the structural phenotype is more subtle and the auditory brainstem response (ABR) thresholds are raised by 25–40 dB across the hearing range, with the greatest loss being in the mid (10–35 kHz) frequency range (28). Here, TECTA is linked to deafness.