All lines exhibited a mild decrease in body weight, but the highest overexpression of miR-184 (∼100-fold in Tg-04 and 32) resulted in severe hyperglycemia and reduced systemic insulin levels, whereas a 5-fold increase (Tg-96) induced glucose intolerance and impaired insulin release (Figures S3L–S3Q). The gene discussed is INS; the disease is Hyperglycemia.