There is ambiguity regarding association of SLC22A11 and SLC22A12 with gout - previous reports have studied different population groups, with various methods for determination of gout; clinical ascertainment using 1977 American Rheumatism Association (ARA) criteria [15,17], self-report of physician-diagnosed gout, use of gout medications [2,18], a combination of self-report and examination of medical records [16]. The gene discussed is SLC22A12; the disease is gout.