ZBTB16 and acute promyelocytic leukemia: The promyelocytic leukemia zinc finger (Plzf) is a kruppel-like C2H2 zinc finger gene which is previously identified in a rare case of acute promyelocytic leukemia (APL) with a variant chromosomal translocation t(11:17) (q23;q21) and resistance to therapy with all-trans-retinoic acid (ATRA) [8].