PLA2G7 and diabetes mellitus: This finding, albeit in different experimental conditions, is in line with a recent paper showing that a synthesized oxidized phospholipid was able to up-regulate Lp-PLA2 mRNA expression in THP-1 cells [10], and also with a porcine model of diabetes demonstrating up-regulation of Lp-PLA2 mRNA expression by PBMC in the presence of advanced glycation end products [39].