A recent study performed by the group of Murray identified CYP1B1 activity in renal cell carcinoma using an activity assay based on the O-deethylation of 7-ethoxyresorufin and the use of the CYP1A1/CYP1B1 inhibitor α-napthoflavone [47]. Here, CYP1B1 is linked to hereditary clear cell renal cell carcinoma.