CYP1B1 and colonic neoplasm: When mean expression levels of CYP1A1 and CYP1B1 mRNA were compared in the entire panel of bladder or colon tissues the analysis indicated that expression levels of CYP1A1 and CYP1B1 mRNA were higher in bladder and colon tumors compared to normal tissues (p < 0.05, Figure 3A and B).