S100A8 and lipoid nephrosis: To understand the clinical implication of MRP8 expression in humans, we have carried out immunohistochemical analysis of MRP8 expression in renal biopsy samples from patients with DN, obesity-related glomerulopathy (ORG) and non-obese, non-diabetic controls (which are minor glomerular abnormality [MGA] and minimal change nephrotic syndrome [MCNS]).