The specific search terms for diabetes, hyperlipidemia, obesity and hyperprolactinemia were “diabetes”, “hyperlipidemia” or “dyslipidemias”, “obesity” or “obese” or “overweight”, “hyperprolactinemia” or “prolactinoma” or “prolactin” respectively. The gene discussed is PRL; the disease is obesity due to melanocortin 4 receptor deficiency.