True SAAs are more common and most seen in patients with atherosclerosis, liver cirrhosis complicated with PHTN, or multiple pregnancies, whereas pseudo SAAs are manifested as complications of previous trauma, pancreatitis or infective endocarditis.2,3 Patients with liver cirrhosis accounted for approximate 20% of the total SAAs cases.2 The number and size of the SAAs vary greatly between patients. The gene discussed is PCSK1N; the disease is cirrhosis of liver.