Allergic rhinitis is a chronic disease of seasonal and/or perennial course, characterized with antibody immunoglobulin E (IgE) mediated inflammation of nasal mucosa triggered by allergens including pollens, dust, foods, mites, animal dander, occupational allergens and drugs.1 European prevalence of the disease varies between 17% and 29%2, while the reported prevalence rate in Turkey is 17.5 %.3 AR is an allergic disease in which production of the antibody IgE as a response to the trigger allergens is the key in the pathogenesis of the disease. This evidence concerns the gene IGHE and allergic disease.