IGHE and migraine disorder: However, the number of studies assessing migraine in AR is limited.11,16,17 Davey at al. emphasized the association between migraine and bronchial asthma,11 while Mortimer et al. reported a higher prevalence of migraine in children with atopy, when compared with children without atophy(atopy).16 A previous study evaluating the possible effects of migraine on allergy investigated the serum IgE and histamine levels during migraine attacks and remission periods in migraine patients with allergy and without allergy.