Consistent with previous findings, we observed significant association among hsCRP, BMI, WHR, BF% & BFM in Saudis.24-26 Unlike most other adipocytederived hormones, circulating adiponectin levels are decreased in obesity.27,28 Adiponectin increases fatty acid oxidation and directly sensitizes the body to insulin.29,30. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.